BrainGB: A Benchmark for Brain Network Analysis with Graph Neural Networks

Overview of BrainGB framework for brain network analysis with graph neural networks.
Publication
Under Review

Mapping the connectome of the human brain using structural or functional connectivity has become one of the most pervasive paradigms for neuroimaging analysis. Recently, Graph Neural Networks (GNNs) motivated from geometric deep learning have attracted broad interest due to their established power for modeling complex networked data. Despite their established performance in other fields, there has not yet been a systematic study of how to design effective GNNs for brain network analysis. To bridge this gap, we present BrainGB, a benchmark for brain network analysis with GNNs. BrainGB standardizes the process by 1) summarizing brain network construction pipelines for both functional and structural neuroimaging modalities and 2) modularizing the implementation of GNN designs. We conduct extensive experiments on datasets across cohorts and modalities and recommend a set of general recipes for effective GNN designs on brain networks. To support open and reproducible research on GNN-based brain network analysis, we also host the BrainGB website with models, tutorials, examples, as well as an out-of-box Python package. We hope that this work will provide useful empirical evidence and offer insights for future research in this novel and promising direction.

Hejie Cui
Hejie Cui
Doctoral Student in CS

My research interests include graph machine learning and knowledge graphs.

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